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Publications of Miki Akamatsu

Books and review

  • Akamatsu, M., Ozoe, Y., Higata, T., Ikeda, I., Mochida, K., Koike, K., Ohmoto, T., Nikaido, T., and Ueno, T.: QSAR studies of picrodendrins and related terpenoids – structural differences between antagonist binding sites on GABA receptors of insects and mammals. In Molecular Modeling and Prediction of Bioactivity (Proceedings of the 12th European Symposium on Quantitative Structure-Activity Relationships: Molecular Modeling and Prediction of Bioactivity) (Eds. Gundertofte, K. and Jorgensen, F.S.), Kluwer Academic/Plenum Publishers, New York, pp. 263-264 (2000)
  • Akamatsu, M.: Current state and perspectives of 3D-QSAR. Current Topics in Med. Chem., 2, 1381-1394 (2002)
  • Akamatsu, M.: 3D Structure-activity relationships of pesticides. J. Pestic. Sci., 27，169-178 (2002) (in Japanese)
  • Mizokami, S., H. Tamamura, K. Hiramatsu, M. Mizumoto, M. Akamatsu, H. Nakashima, Z. Wang, S.C. Peiper, N. Yamamoto, A. Otaka and N. Fujii: New leads of low molecular weight CXCR4 antagonists based on enhancement of the T140-based pharmacophores. Peptide Science 2003(Ed. M. Ueki), pp. 285-288, The Japanese Peptide Society, Tsukuba, (2004)
  • Miyashita, M., T.Shimada, S. Nakagami, N. Kurihara, H. Miyagawa and M. Akamatsu: Evaluation of estrogen receptor binding affinity of DDT-related compounds and their metabolites. Environmental Fate and Safety Management of Agrochemicals (Eds. J.M. Clark, and H. Ohkawa), pp. 159-166, American Chemical Society, Washington, DC, (2005)
  • Akamatsu, M., Fujikawa, M., Ano, R., Nakao, K., and Shimizu, R.: Relationships between structure and high-throughput screening permeability of diverse drugs with artificial membranes: application to prediction of Caco-2 cell permeability. In QSAR & Molecular Modelling in Rational Design of Bioactive Molecules (Proceedings of the 15th EuroQSAR 2004 Symposium) (Eds. Aki, E. and Yalcin, I.), Baskent Klise ve Matbaacilik, Ankara, pp. 166-167 (2006)
  • Tamura, H., Hosoda, A., and Akamatsu, M.: Endocrine disruptors that disrupt the transcription mediated by androgen receptor. J. Pestic. Sci., 33, 33-39 (2008)

 

Original article

  • Shimomura, M., Okuda, H., Matsuda, K., Komai, K., Akamatsu, M., and Sattelle, D.B.: Effects of mutations of a glutamine residue in loop D of the a7 nicotinic acetylcholine receptor on agonist profiles for neonicotinoid insecticides and related ligands. British J. Pharm., 137, 162-169 (2002)
  • Yamagami, C., Motohashi, N., and Akamatsu, M.: Quantum chemical- and 3-D-QSAR (CoMFA) studies of benzalacetones and 1,1,1-trifluoro-4-phenyl-3-buten-2-ones. Bioorg. Med. Chem. Lett., 12, 2281-2285 (2002)
  • Ano, R., Kimura, Y., Shima, M., Matsuno, R., and Akamatsu, M.: Relationship between Structure and Permeability of Oligopeptides and Related Compounds. In Peptide Science 2002(Ed. T. Yamada), The Japanese Peptide Society, pp. 233-234 (2003)
  • Akamatsu, M., Ano, R., Kimura, Y., Shima, M., and Matsuno, R: Relationship between structure and permeability of oligopeptide derivatives and related compounds. In Designing Drugs and Crop Protectants: processes, problems, and solutions (Proceedings of the 14th EuroQSAR 2002 Symposium) (Eds. Ford, M., Livingstone, D., Dearden, J., and Waterbeemd, H. van de), Blackwell Publishing, Oxford, pp. 224-225 (2003).
  • Yamagami, C., Motohashi, N., Emoto, T., Tanahashi, T., Nagakura, N., Akamatsu, M., and Takeuchi, Y.: Quantitative structure-activity relationship analyses of antioxidative hydroxybenzalacetones. In Designing Drugs and Crop Protectants: processes, problems, and solutions (Proceedings of the 14th EuroQSAR 2002 Symposium) (Eds. Ford, M., Livingstone, D., Dearden, J., and Waterbeemd, H. van de), Blackwell Publishing, Oxford, pp. 471-472 (2003).
  • Miyashita, M., T. Shimada, S. Nakagami, N. Kurihara, H. Miyagawa. and M. Akamatsu: Enantioselective Recognition of Mono-demethylated methoxychlor metabolites by the estrogen receptor. Chemosphere 54, 1273-1276, (2004)
  • Ano, R., Y. Kimura, M. Urakami, M. Shima, R. Matsuno, T. Ueno and M. Akamatsu: Relationship between structure and permeability of dipeptide derivatives containing Tryptophan and related compounds across human intestinal epithelial (Caco-2) cells. Bioorg. Med. Chem. 12, 249-255, (2004)
  • Ano, R., Y. Kimura, M. Shima, R. Matsuno, T. Ueno and M. Akamatsu: Relationships between structure and high-throughput screening permeability of peptide derivatives and related compounds with artificial membranes: application to prediction of Caco-2 cell permeability. Bioorg. Med. Chem. 12, 257-264, (2004)
  • Wanchana, S, F. Yamashita, H. Hara, S. Fujiwara, M. Akamatsu and M. Hashida: Two- and three-dimensional QSAR of carrier-mediated transport of ?-lactam antibiotics in Caco-2 cells. J. Pharm. Sci. 93, 3057-3065,(2004)
  • Miyashita, M., T.Shimada, S. Nakagami, N. Kurihara, H. Miyagawa and M. Akamatsu: Evaluation of estrogen receptor binding affinity of DDT-related compounds and their metabolites. Environmental Fate and Safety Management of Agrochemicals (Eds. J.M. Clark, and H. Ohkawa), pp. 159-166, American Chemical Society, Washington, DC, (2005)
  • Yamamoto, S., Watanabe, B., Otsuki, J., Nakagawa, Y., Akamatsu, M, and Miyagawa, H.: Synthesis of 26, 27-bisnorcastasterone analogs and analysis of conformation-activity relationship for brassinolide-like activity. Bioorg. Med. Chem., 14, 1761-1770 (2006).
  • Wheelock, C.E., Nakagawa, Y., Harada, T., Oikawa, N., Akamatsu, M., Smagghe, G., Stefanou, D., Iatrou, K., and Swevers, L.: High-throughput screening of ecdyson agonists using a reporter gene assay followed by 3-D QSAR analysis of the molting hormonal activity. Bioorg. Med. Chem., 14, 1143-1159 (2006).
  • Minakuchi, C., Suzuki, J., Toda, K., Akamatsu, M., and Nakagawa, Y.: Estimation of the hydrophobicity of 2,4-diphenyl-1,3-oxazoline analogs and QSAR analysis of their ovicidal activity against Tetranycus urticae. Bioorg. Med. Chem. Lett., 16, 4080-4084 (2006).
  • Tamura, H., Ishimoto, Y., Fujikawa, T., Aoyama, H., Yoshikawa, H., and Akamatsu, M.: Structural basis for androgen receptor agonists and antagonists: Interaction of SPEED 98-listed chemicals and related compounds with the androgen receptor based on an in vitro reporter gene assay and 3D-QSAR. Bioorg. Med. Chem., 14, 7160-7174 (2006).
  • Shimomura, M., Yokota, M., Ihara, M., Akamatsu, M., Sattelle, D.B., and Matsuda, K.: Role in the selectivity of neonicotinoids of insect-specific basic residues in loop D of the nicotinic acetylcholine receptor agonist binding site. Mol. Pharmacol., 70, 1255-1263 (2006).
  • Fujikawa, M., Nakao, K., Shimizu, R., and Akamatsu, M.: QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorg. Med. Chem., 15, 3756-3767 (2007).
  • Tomita, K., Oishi, S., Cluzeau, J., Ohno, H., Navenot, J.-M., Wang, Z., Peiper, S.C., Akamatsu, M., and Fujii, N.: SAR and QSAR studies on the N-terminally acylated pentapeptide agonists for GPR54. J. Med. Chem., 50, 3222-3228 (2007).
     

 

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